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Article published on the 2008-08-05 Latest update 2008-08-05 09:13 TU
Lee's decision to lift a five-year ban on US beef has sparked a massive backlash in the country, with demonstrators saying the agreement does not protect them against mad cow disease, or BSE.
As well as the recent controversy over beef imports, Bush is also expected to discuss efforts to end North Korea's nuclear weapons drive and free-trade legislation with Lee.
Protests over the beef imports had started to die down, after Seoul won some promises of safeguards from Washington that meat from older cattle would not be exported to South Korea.
However, organisers say they expect at least 10,000 people to attend a rally tonight in Seoul.
US beef imports resumed on 29 July, although many larger South Korean shops and restaurants still refuse to serve the meat.
The US president is later set to deliver a major foreign policy speech in Thailand, where he is expected to condemn the military government of Myanmar, for human rights abuses.
He will then go on to the opening of the Olympic Games in Beijing.